AB blood group

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The AB blood group is displayed in individuals whose red blood cells display both the A and B antigen. This is a rare blood group type, AB negative being the rarest[1].

The ABO gene encodes for the formation of glycosyltransferases that add N-acetylgalactosamine and galactose to the H antigen already present on the red blood cells, to form both A and B antigens[2].

The individual with the AB blood type does not contain any antibodies against A and B antigens. This is so the immune system does not attack the red blood cells[3].

References

  1. Dean L. Bethesda, blood groups and red cell antigens, 2005,5 [1]
  2. Victor A. McKusick,ABO GLYCOSYLTRANSFERASE; ABO , 1986,OMIM entry description. [2]
  3. Marius Lixandru, What are blood types and what do they mean?, Natureworld, 2008 [3]
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