Islets of Langerhans: Difference between revisions
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These are arranged in bundles in the [[Endocrine|endocrine]] region of the [[Pancreas|pancreas]] | These are arranged in bundles in the [[Endocrine|endocrine]] region of the [[Pancreas|pancreas]] and they consist of alpha and [[Beta cell|beta cells]]. The alpha cells release [[Glucagon|glucagon]] which results in an increase in [[Blood|blood]] [[Glucose|glucose]] concentration. Glucagon causes the [[Liver|liver]] to convert [[Glycogen|glycogen]] into glucose by [[Hydrolysis|hydrolysis]]. The beta cells secrete the hormone molecule [[Insulin|insulin]] which has the opposite effect of glucagon by decreasing blood glucose [[Concentration|concentration]]. [[Insulin|Insulin]] binds to membrane-bound receptors on target cells, allowing [[Facilitated diffusion|facilitated diffusion]] of [[Glucose|glucose]] into the cells. It also activates the enzyme [[Glycogen synthase|glycogen synthetase]] which converts [[Glucose|glucose]] into [[Glycogen|glycogen]] for storage <ref>Fox, S.I., 2011. Human Physiology. 12th ed. New York: McGraw-Hill</ref>.<br> | ||
=== References === | === References === | ||
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Latest revision as of 16:39, 30 November 2012
These are arranged in bundles in the endocrine region of the pancreas and they consist of alpha and beta cells. The alpha cells release glucagon which results in an increase in blood glucose concentration. Glucagon causes the liver to convert glycogen into glucose by hydrolysis. The beta cells secrete the hormone molecule insulin which has the opposite effect of glucagon by decreasing blood glucose concentration. Insulin binds to membrane-bound receptors on target cells, allowing facilitated diffusion of glucose into the cells. It also activates the enzyme glycogen synthetase which converts glucose into glycogen for storage [1].
References
- ↑ Fox, S.I., 2011. Human Physiology. 12th ed. New York: McGraw-Hill