Cytotoxic T-cells: Difference between revisions
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Cytotoxic T cells are able to search the [[Intracellular compartment|intracellular compartments]] to remove or destroy any foreign objects such as [[Bacteria|bacteria]] and pathogens which have the potential to cause harm. Also known as a killer T-cell or CD8+ T cells. These cells kill host cells that have become infected by some sort of intracellular [[Pathogen|pathogen]]<ref>alberts, B (2008). molecular biology of the cell. USA: garland science. glossary</ref>. | |||
<ref>alberts, B (2008). molecular biology of the cell. USA: garland science. glossary</ref> | |||
The cytotoxic T-cells can trigger an endogenous pathway within the target cell leading to [[Apoptosis|apoptosis]]. This is due to the cytotoxic T-cells releasing "preformed effector molecules"<ref>Janeway CA Jr, et al.;2001</ref><ref>Janeway C. Immunobiology. 5th ed. Paris: De Boeck; 2003.</ref>. | |||
Cytotoxic T-cells contain the CD8+ receptor. They are responsible for binding [[MHC Molecules|MHC class I]] present in most cells, which presents the foreign antigen of the endogenous origin<ref>https://www.ncbi.nlm.nih.gov/books/NBK27101/</ref>. | |||
=== References === | |||
<references /> | |||
Latest revision as of 02:23, 29 October 2018
Cytotoxic T cells are able to search the intracellular compartments to remove or destroy any foreign objects such as bacteria and pathogens which have the potential to cause harm. Also known as a killer T-cell or CD8+ T cells. These cells kill host cells that have become infected by some sort of intracellular pathogen[1].
The cytotoxic T-cells can trigger an endogenous pathway within the target cell leading to apoptosis. This is due to the cytotoxic T-cells releasing "preformed effector molecules"[2][3].
Cytotoxic T-cells contain the CD8+ receptor. They are responsible for binding MHC class I present in most cells, which presents the foreign antigen of the endogenous origin[4].
References
- ↑ alberts, B (2008). molecular biology of the cell. USA: garland science. glossary
- ↑ Janeway CA Jr, et al.;2001
- ↑ Janeway C. Immunobiology. 5th ed. Paris: De Boeck; 2003.
- ↑ https://www.ncbi.nlm.nih.gov/books/NBK27101/