Point mutation: Difference between revisions
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Created page with " A point mutation refers to a substitution of a single base nucleotide in a sequence of DNA or RNA. The effects of this may be [[Silent mutation|silen..." |
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A point mutation refers to a substitution of a single base [[Nucleotide|nucleotide]] in a sequence of [[DNA|DNA]] or RNA. The effects of this may be [[Silent mutation|silent]] (in which after the substitution, the sequence still codes for the same [[Amino acid|amino acid]] due to the [[The genetic code|genetic code]] being degenerate), [[Nonsense mutation|nonsense]] (the substitution leads to the sequence coding for a [[Stop codon|stop codon]]) or [[Missense mutation|missense]] (the substitution leads to the sequence coding for a different amino acid which may have similar or different properties and alter the functionality of the polypeptide) <ref>Ghr.nlm.nih.gov. 2013. Point mutation - Glossary Entry - Genetics Home Reference. [online] Available at: http://ghr.nlm.nih.gov/glossary=pointmutation [Accessed: 8 Nov 2013].</ref>. | |||
<br> | [[Image:Point mutations-en.png]]<ref>Image from: http://conradchrabol.files.wordpress.com/2012/12/2-4.png?w=694&amp;h=367</ref><br> | ||
=== References === | === References === | ||
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Latest revision as of 04:33, 9 November 2013
A point mutation refers to a substitution of a single base nucleotide in a sequence of DNA or RNA. The effects of this may be silent (in which after the substitution, the sequence still codes for the same amino acid due to the genetic code being degenerate), nonsense (the substitution leads to the sequence coding for a stop codon) or missense (the substitution leads to the sequence coding for a different amino acid which may have similar or different properties and alter the functionality of the polypeptide) [1].
References
- ↑ Ghr.nlm.nih.gov. 2013. Point mutation - Glossary Entry - Genetics Home Reference. [online] Available at: http://ghr.nlm.nih.gov/glossary=pointmutation [Accessed: 8 Nov 2013].
- ↑ Image from: http://conradchrabol.files.wordpress.com/2012/12/2-4.png?w=694&h=367
