Introns: Difference between revisions
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Introns are non-coding sequences of [[DNA|DNA]] found between coding sections known as [[Exons|exons]] in [[Eukaryotic|eukaryotic]] [[Gene|genes]] and in rare cases in some [[Prokaryotes|prokaryotic cells]] <ref>Khan AU, Ajamaluddin M, Ahmad M.(2001 Oct) A unique group of self-splicing introns in bacteriophage T4. Indian J Biochem Biophys. 38(5):289-93 | <ref>Rev. Biochem. 1995. 64:435</ref>Introns are non-coding sequences of [[DNA|DNA]] found between coding sections known as [[Exons|exons]] in [[Eukaryotic|eukaryotic]] [[Gene|genes]] and in rare cases in some [[Prokaryotes|prokaryotic cells]] <ref>Khan AU, Ajamaluddin M, Ahmad M.(2001 Oct) A unique group of self-splicing introns in bacteriophage T4. Indian J Biochem Biophys. 38(5):289-93.</ref>. | ||
Introns nearly always have a consensus sequence that begins with GU and ends with AG which is preceeeded by a pyrimidine rich tract that acts as a signal for splicing. <ref>Berg, J., Tymoczko, J. and Stryer, L. 2012. Biochemistry. Basingstoke: W. H. Freeman. P136</ref> | Introns are removed by [[Rna splicing|splicing]] by the [[Spliceosome|spliceosome]] and other associated proteins that are recruited in the process of forming mature [[MRNA|mRNA]] from pre-mRNA <ref>Hogg R, McGrail JC, O'Keefe RT.(Aug 2010) The function of the NineTeen Complex (NTC) in regulating spliceosome conformations and fidelity during pre-mRNA splicing. Biochem Soc Trans. 38(4):1110-5.</ref>. | ||
Introns nearly always have a consensus sequence that begins with GU and ends with AG which is preceeeded by a [[Pyrimidine|pyrimidine]] rich tract that acts as a signal for splicing. <ref>Berg, J., Tymoczko, J. and Stryer, L. 2012. Biochemistry. Basingstoke: W. H. Freeman. P136</ref> | |||
There are 3 Kind of Introns: Group I, II and III Group II are [[ribozymes|ribozymes]] with self catalytic activities which utilize self splicing. | |||
=== References === | === References === | ||
<references /> | <references /> | ||
Latest revision as of 02:41, 30 October 2015
[1]Introns are non-coding sequences of DNA found between coding sections known as exons in eukaryotic genes and in rare cases in some prokaryotic cells [2].
Introns are removed by splicing by the spliceosome and other associated proteins that are recruited in the process of forming mature mRNA from pre-mRNA [3].
Introns nearly always have a consensus sequence that begins with GU and ends with AG which is preceeeded by a pyrimidine rich tract that acts as a signal for splicing. [4]
There are 3 Kind of Introns: Group I, II and III Group II are ribozymes with self catalytic activities which utilize self splicing.
References
- ↑ Rev. Biochem. 1995. 64:435
- ↑ Khan AU, Ajamaluddin M, Ahmad M.(2001 Oct) A unique group of self-splicing introns in bacteriophage T4. Indian J Biochem Biophys. 38(5):289-93.
- ↑ Hogg R, McGrail JC, O'Keefe RT.(Aug 2010) The function of the NineTeen Complex (NTC) in regulating spliceosome conformations and fidelity during pre-mRNA splicing. Biochem Soc Trans. 38(4):1110-5.
- ↑ Berg, J., Tymoczko, J. and Stryer, L. 2012. Biochemistry. Basingstoke: W. H. Freeman. P136