Transposon: Difference between revisions
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Added more information about transposons eg. classes, removed repeat reference. |
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Transposons are [[Gene|genes]] that can move. They have a specific target site,allowing them to move or 'jump' into different [[DNA|DNA]] sites<ref>Bruce Alberts,Alexander Johnson,Julian Lewis,Martin Raff,Keith Roberts and Peter Walter (2002) Molecular Biology Of The Cell,4th edition,New York: Garland Science.p287</ref>. Transposons leave copies of themselves wherever they stop. Half of the [[Human genome|human genom]][[Human genome|e]] consists of these 'jumping genes'<ref>Hardin, J. Bertoni, G. Kleinsmith, L (2012). Becker's World of the Cell. 8th ed. San Francisco: Pearson: 527</ref>. They are important for genomic variation and [[Evolution|evolution]] in organisms. Transposons are subdivided into 2 classes: | |||
*'''Class I transposons''' - also called retrotransposons - they make up 40% of the human genome. They move from one genome to another via a 'copy and paste' mechanism in which an RNA intermediate is transcribed from the retrotransposon, then made into cDNA via [[Reverse transcriptase|reverse transcriptase]] where it binds to the recipient DNA. The original genomic region containing the retrotransposon is not deleted. | *'''Class I transposons''' - also called [[retrotransposons|retrotransposons]] - they make up 40% of the human genome. They move from one genome to another via a 'copy and paste' mechanism in which an RNA intermediate is transcribed from the retrotransposon, then made into cDNA via [[Reverse transcriptase|reverse transcriptase]] where it binds to the recipient DNA. The original genomic region containing the retrotransposon is not deleted. | ||
*'''Class II transposons - '''move from one genome to another via a 'cut and paste' mechanism<ref>Kimball’s Biology Pages. Transposons: Mobile DNA. 2018 [cited 15/11/18]; Available From: http://www.biology-pages.info/T/Transposons.html</ref>. | *'''Class II transposons - '''move from one genome to another via a 'cut and paste' mechanism<ref>Kimball’s Biology Pages. Transposons: Mobile DNA. 2018 [cited 15/11/18]; Available From: http://www.biology-pages.info/T/Transposons.html</ref>. | ||
=== References === | |||
<references /> | <references /> | ||
Revision as of 17:34, 6 December 2018
Transposons are genes that can move. They have a specific target site,allowing them to move or 'jump' into different DNA sites[1]. Transposons leave copies of themselves wherever they stop. Half of the human genome consists of these 'jumping genes'[2]. They are important for genomic variation and evolution in organisms. Transposons are subdivided into 2 classes:
- Class I transposons - also called retrotransposons - they make up 40% of the human genome. They move from one genome to another via a 'copy and paste' mechanism in which an RNA intermediate is transcribed from the retrotransposon, then made into cDNA via reverse transcriptase where it binds to the recipient DNA. The original genomic region containing the retrotransposon is not deleted.
- Class II transposons - move from one genome to another via a 'cut and paste' mechanism[3].
References
- ↑ Bruce Alberts,Alexander Johnson,Julian Lewis,Martin Raff,Keith Roberts and Peter Walter (2002) Molecular Biology Of The Cell,4th edition,New York: Garland Science.p287
- ↑ Hardin, J. Bertoni, G. Kleinsmith, L (2012). Becker's World of the Cell. 8th ed. San Francisco: Pearson: 527
- ↑ Kimball’s Biology Pages. Transposons: Mobile DNA. 2018 [cited 15/11/18]; Available From: http://www.biology-pages.info/T/Transposons.html