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==== Introduction ====
==== Introduction ====
 
The Krebs Cycle can also be called the Citric Acid Cycle (CAC) or the Tricarboxylic Acid (TCA) Cycle. This cycle takes place in the matrix of [[Mitochondria|mitochondria ]]and is the first step of aerobic processing in the cell. The process oxidises glucose derivatives as well as fatty acids and amino acids to carbon dioxide (CO<sub>2</sub>), most of which enter the cycle as [[acetyl coenzyme A|acetyl coenzyme A]]. The purpose of the Krebs Cycle is to collect (eight) high-energy electrons from these fuels, which are carried by [[NADH|NADH ]]and [[FADH2|FADH<sub>2</sub>]] to the electron transport chain. The Krebs Cycle is also the source of the precursors of many other molecules and is therefore amphibolic which means that it is both an anabolic and a catabolic pathway. <ref>Berg J.M, Tymoczko J.L, Stryer, L (2007). Biochemistry. 6th ed. New York: W. H. Freeman and Company. p475-476.</ref>
 


The Krebs Cycle can also be called the Citric Acid Cycle (CAC) or the Tricarboxylic Acid (TCA) Cycle. This cycle takes place in the matrix of [[Mitochondria|mitochondria]] and&nbsp;is the first step of aerobic processing in the cell. The process [[oxidation|oxidises]] glucose derivatives, fatty acids and amino acids to carbon dioxide (CO<sub>2</sub>) through a series of [[Enzyme|enzyme]] controlled steps. The purpose of the Krebs Cycle is to collect (eight) high-energy electrons from these fuels by oxidising them, which are carried by [[NADH|NADH and]] [[FADH2|FADH<sub>2</sub>]] to the [[electron transport chain|electron transport chain]]. The Krebs Cycle is also the source for the precursors of many other molecules and is therefore an amphibolic pathway (meaning it is both anabolic and catabolic).&nbsp;


=== The 8 Steps of the Krebs Cycle ===
=== The 8 Steps of the Krebs Cycle ===


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Revision as of 16:13, 8 January 2011

Introduction

The Krebs Cycle can also be called the Citric Acid Cycle (CAC) or the Tricarboxylic Acid (TCA) Cycle. This cycle takes place in the matrix of mitochondria and is the first step of aerobic processing in the cell. The process oxidises glucose derivatives, fatty acids and amino acids to carbon dioxide (CO2) through a series of enzyme controlled steps. The purpose of the Krebs Cycle is to collect (eight) high-energy electrons from these fuels by oxidising them, which are carried by NADH and FADH2 to the electron transport chain. The Krebs Cycle is also the source for the precursors of many other molecules and is therefore an amphibolic pathway (meaning it is both anabolic and catabolic). 

The 8 Steps of the Krebs Cycle

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