Glycerine: Difference between revisions
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Glycerine (also known as Glycerol or Glycerin) is a colourless, viscous, oudourless fluid that is mainly used in pharmaceutical companies. Due to its sweet taste and low toxicity it is ideal for cough syrups and other medicines. | Glycerine (also known as Glycerol or Glycerin) is a colourless, viscous, oudourless fluid that is mainly used in pharmaceutical companies. Due to its sweet taste and low toxicity it is ideal for cough syrups and other medicines. | ||
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STURUCTURE | |||
Glycerol contains 3 hydroxyl groups, these make it water soluble. | |||
It's molecular formula is CH2(OH)CH(OH)CH2OH | |||
PRODUCTION | |||
Glycerol is mainly produced as a byproduct in other processes such as saponification of fats (soap making) as Glycerol forms the core of trigycerides. | |||
It is also produced as a byproduct in biodiesel production. | |||
METABOLISM | |||
Gluconeogenisis in the liver is when the body uses Glycerol to make [[Glucose|Glucose]] in fasting conditions. | |||
Glycerol is one of the 3 main carbon sources in the body for gluconeogenisis. The Glycerol is released from the adipose stores of triacylglycerol and phosphorylated into Glycerol-3-P which is then converted to Dihydroxyacetone-P which goes onto produce Glucose. <ref>Marks, L., Marks' Basic Medical Biochemistry A Clinical Approach, 4th Edition, page 562.</ref> | |||
Revision as of 12:21, 23 October 2012
Glycerine (also known as Glycerol or Glycerin) is a colourless, viscous, oudourless fluid that is mainly used in pharmaceutical companies. Due to its sweet taste and low toxicity it is ideal for cough syrups and other medicines.
STURUCTURE
Glycerol contains 3 hydroxyl groups, these make it water soluble.
It's molecular formula is CH2(OH)CH(OH)CH2OH
PRODUCTION
Glycerol is mainly produced as a byproduct in other processes such as saponification of fats (soap making) as Glycerol forms the core of trigycerides.
It is also produced as a byproduct in biodiesel production.
METABOLISM
Gluconeogenisis in the liver is when the body uses Glycerol to make Glucose in fasting conditions.
Glycerol is one of the 3 main carbon sources in the body for gluconeogenisis. The Glycerol is released from the adipose stores of triacylglycerol and phosphorylated into Glycerol-3-P which is then converted to Dihydroxyacetone-P which goes onto produce Glucose. [1]
- ↑ Marks, L., Marks' Basic Medical Biochemistry A Clinical Approach, 4th Edition, page 562.