Glycerine: Difference between revisions

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Glycerine (also known as Glycerol or Glycerin) is a colourless, viscous, oudourless fluid that&nbsp;is mainly used in pharmaceutical companies. Due to its sweet taste and low toxicity it is ideal for cough syrups and other medicines.<br>  
Glycerine (also known as Glycerol or Glycerin) is a colourless, viscous, odourless fluid that&nbsp;is mainly used in pharmaceutical companies. Due to its sweet taste and low toxicity it is ideal for cough syrups and other medicines.<br>  


=== Structure ===
=== Structure ===


Glycerol contains 3 [[hydroxyl group|hydroxyl groups]], these make it [[water|water]] soluble.  
Glycerol contains 3 [[Hydroxyl group|hydroxyl groups]], which make it [[Water|water]] soluble.  


It's molecular formula is CH2(OH)CH(OH)CH2OH<br>  
Its molecular formula is CH2(OH)CH(OH)CH2OH<br>  


=== Production ===
=== Production ===


Glycerol is mainly produced as a byproduct in other processes such as saponification&nbsp;of fats&nbsp;(soap making) as [[glycerol|glycerol]] forms the core of [[triglycerides|triglycerides]].  
Glycerol is mainly produced as a byproduct in other processes, such as saponification&nbsp;of fats&nbsp;(soap making), as [[Glycerol|glycerol]] forms the core of [[Triglycerides|triglycerides]].  


It is also produced as a byproduct in biodiesel production.<br>  
It is also produced as a byproduct in biodiesel production.<br>  


=== Metabolism ===
=== Metabolism ===


Gluconeogenisis in the [[liver|liver]] is when the body uses [[glycerol|glycerol]] to make [[glucose|glucose]] in fasting conditions.  
Gluconeogenisis occurs in the [[Liver|liver]], and&nbsp;is when the body uses [[Glycerol|glycerol]] to make [[Glucose|glucose]] in fasting conditions.  


Glycerol is one of the 3 main carbon sources in the body for [[gluconeogenesis|gluconeogenesis]].&nbsp;The glycerol is released from the adipose stores of [[triacylglycerol|triacylglycerol]] and [[Phosphorylation|phosphorylated]] into [[glycerol-3-P|glycerol-3-P]] which is then converted to [[dihydroxyacetone-P|dihydroxyacetone-P]] which goes onto produce [[glucose|glucose]]&nbsp;<ref>Marks, L., Marks' Basic Medical Biochemistry A Clinical Approach, 4th Edition, page 562.</ref>.
Glycerol is one of the 3 main carbon sources in the body for [[Gluconeogenesis|gluconeogenesis]].&nbsp;The glycerol is released from the adipose stores of [[Triacylglycerol|triacylglycerol]] and [[Phosphorylation|phosphorylated]] into [[Glycerol-3-P|glycerol-3-P]]. Glycerol-3-P is then converted to [[Dihydroxyacetone-P|dihydroxyacetone-P]], which&nbsp;then&nbsp;produces&nbsp;[[Glucose|glucose]]&nbsp;<ref>Marks, L., Marks' Basic Medical Biochemistry A Clinical Approach, 4th Edition, page 562.</ref>.  


=== References ===
=== References ===


<references />
<references />

Revision as of 16:05, 3 December 2017

Glycerine (also known as Glycerol or Glycerin) is a colourless, viscous, odourless fluid that is mainly used in pharmaceutical companies. Due to its sweet taste and low toxicity it is ideal for cough syrups and other medicines.

Structure

Glycerol contains 3 hydroxyl groups, which make it water soluble.

Its molecular formula is CH2(OH)CH(OH)CH2OH

Production

Glycerol is mainly produced as a byproduct in other processes, such as saponification of fats (soap making), as glycerol forms the core of triglycerides.

It is also produced as a byproduct in biodiesel production.

Metabolism

Gluconeogenisis occurs in the liver, and is when the body uses glycerol to make glucose in fasting conditions.

Glycerol is one of the 3 main carbon sources in the body for gluconeogenesis. The glycerol is released from the adipose stores of triacylglycerol and phosphorylated into glycerol-3-P. Glycerol-3-P is then converted to dihydroxyacetone-P, which then produces glucose [1].

References

  1. Marks, L., Marks' Basic Medical Biochemistry A Clinical Approach, 4th Edition, page 562.