T cells: Difference between revisions
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T-cells or T-lymphocytes are a group of lymphocytes involved in specific immune response, specificlly antigen-specific cellular interactions. There are two main subsets; [[Cytotoxic T-cells|Cytotoxic T-cells]] and [[Helper T-cells|Helper T-cells]], Helper T-cells are further divided into inflammatory ([[TH1|TH1]]) and ([[TH2|TH2]]) Helper cells which asssist [[B-cells|B-cells]] by forming [[ | T-cells or T-lymphocytes are a group of lymphocytes involved in specific immune response, specificlly antigen-specific cellular interactions. There are two main subsets; [[Cytotoxic T-cells|Cytotoxic T-cells]] and [[Helper T-cells|Helper T-cells]], Helper T-cells are further divided into inflammatory ([[TH1|TH1]]) and ([[TH2|TH2]]) Helper cells which asssist [[B-cells|B-cells]] by forming [[Antibody|antibodies]]. T-cells are formed from bone marrow stem cells that undergo maturation in the [[Thymus|Thymus]] <ref name="Brock Biology of Microorganisms">Michael Madigan, John Martinko, David Stahl, David Clark. (2012) Brock Biology of Microorganisms, Thirteenth Edition, San Francisco: Pearson. 246-249</ref>. | ||
Individual T cells are able to recognise only certain antigens, discriminating between antigens using protein molecules on the cell surface called receptors. The receptor and the antigen fit together like a lock and a key only when their shapes match perfectly. The number and specificity of T cell receptors appears to be determined by the cell’s genes <ref>http://www.nationalmssociety.org/What-is-MS/Definition-of-MS/T-cells</ref>. | |||
=== Referneces === | === Referneces === | ||
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Revision as of 13:46, 19 October 2015
T-cells or T-lymphocytes are a group of lymphocytes involved in specific immune response, specificlly antigen-specific cellular interactions. There are two main subsets; Cytotoxic T-cells and Helper T-cells, Helper T-cells are further divided into inflammatory (TH1) and (TH2) Helper cells which asssist B-cells by forming antibodies. T-cells are formed from bone marrow stem cells that undergo maturation in the Thymus [1].
Individual T cells are able to recognise only certain antigens, discriminating between antigens using protein molecules on the cell surface called receptors. The receptor and the antigen fit together like a lock and a key only when their shapes match perfectly. The number and specificity of T cell receptors appears to be determined by the cell’s genes [2].
Referneces
- ↑ Michael Madigan, John Martinko, David Stahl, David Clark. (2012) Brock Biology of Microorganisms, Thirteenth Edition, San Francisco: Pearson. 246-249
- ↑ http://www.nationalmssociety.org/What-is-MS/Definition-of-MS/T-cells