Cytochrome C: Difference between revisions
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Cytochrome C is released from a leaky [[Mitochondria|mitochondria]] in [[Apoptosis|apoptosis]], from the intermembrane space to the cytosol. It activates [[Caspase|caspase]] 9 within the cell. Caspase 9 then activates other [[Caspases|caspases]] within the cell, amplifying the message of [[Apoptosis|apoptosis]] <ref>Berg J, Stryer L, Tymoczko J. (2011) Biochemistry, 7th Edition. International Edition, Basingstoke: Palgrave Macmillan. Page 577.</ref>. | Cytochrome C is released from a leaky [[Mitochondria|mitochondria]] in [[Apoptosis|apoptosis]], from the intermembrane space to the [[Cytosol|cytosol]]. It activates [[Caspase|caspase]] 9 within the cell. Caspase 9 then activates other [[Caspases|caspases]] within the cell, amplifying the message of [[Apoptosis|apoptosis]] <ref>Berg J, Stryer L, Tymoczko J. (2011) Biochemistry, 7th Edition. International Edition, Basingstoke: Palgrave Macmillan. Page 577.</ref>. | ||
It also plays a role in the [[Electron transport chain|electron transport chain]], accepting [[Electrons|electrons]] from complex III and donating them to complex IV.<ref>Alberts et al (2008: 1118) Molecular Biology of the Cell, 5th Edition, New York: Garland Science.</ref><br> | |||
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Latest revision as of 07:07, 22 October 2014
Cytochrome C is released from a leaky mitochondria in apoptosis, from the intermembrane space to the cytosol. It activates caspase 9 within the cell. Caspase 9 then activates other caspases within the cell, amplifying the message of apoptosis [1].
It also plays a role in the electron transport chain, accepting electrons from complex III and donating them to complex IV.[2]
References