Cytochrome C

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Cytochrome C is released from a leaky mitochondria in apoptosis, from the intermembrane space to the cytosol. It activates caspase 9 within the cell. Caspase 9 then activates other caspases within the cell, amplifying the message of apoptosis [1].

It also plays a role in the electron transport chain, accepting electrons from complex III and donating them to complex IV.[2]

References

  1. Berg J, Stryer L, Tymoczko J. (2011) Biochemistry, 7th Edition. International Edition, Basingstoke: Palgrave Macmillan. Page 577.
  2. Alberts et al (2008: 1118) Molecular Biology of the Cell, 5th Edition, New York: Garland Science.



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