Terminator sequence: Difference between revisions
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A terminator sequence is a [[Nucleotide|nucleotide]] sequence in [[DNA]] which ends marks the end of a [[Gene|gene]] during [[Transcription]]. This sequence does this by providing signals that trigger the release of [[MRNA|mRNA]] from the [[Transcription complex|transcription complex]]. This then means that the mRNA can be [[Splicing|spliced]] (if needed) and [[Translation|translated]] into [[Proteins|proteins]]. <ref>http://genesdev.cshlp.org/content/23/11/1247.full</ref> | A terminator sequence is a [[Nucleotide|nucleotide]] sequence in [[DNA]] which ends marks the end of a [[Gene|gene]] during [[Transcription]]. This sequence does this by providing signals that trigger the release of [[MRNA|mRNA]] from the [[Transcription complex|transcription complex]]. This then means that the mRNA can be [[Splicing|spliced]] (if needed) and [[Translation|translated]] into [[Proteins|proteins]] <ref>http://genesdev.cshlp.org/content/23/11/1247.full</ref><ref>Patricia Richard and James L. Manley (2009), Transcription termination by nuclear RNA polymerases. Genes &amp; Dev. 2009. 23: 1247-1269. doi: 10.1101/gad.1792809</ref><ref>http://genesdev.cshlp.org/content/23/11/1247.full</ref>. | ||
In [[Prokaryotic genomes|prokaryotic genomes]] there are two classes of terminators, [[Rho dependent termination|Rho-dependent and]] [[Rho independent terminators|Rho-independent]]. | In [[Prokaryotic genomes|prokaryotic genomes]] there are two classes of terminators, [[Rho dependent termination|Rho-dependent and]] [[Rho independent terminators|Rho-independent]]. | ||
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Latest revision as of 13:08, 19 October 2016
A terminator sequence is a nucleotide sequence in DNA which ends marks the end of a gene during Transcription. This sequence does this by providing signals that trigger the release of mRNA from the transcription complex. This then means that the mRNA can be spliced (if needed) and translated into proteins [1][2][3].
In prokaryotic genomes there are two classes of terminators, Rho-dependent and Rho-independent.
References:
- ↑ http://genesdev.cshlp.org/content/23/11/1247.full
- ↑ Patricia Richard and James L. Manley (2009), Transcription termination by nuclear RNA polymerases. Genes & Dev. 2009. 23: 1247-1269. doi: 10.1101/gad.1792809
- ↑ http://genesdev.cshlp.org/content/23/11/1247.full