Terminator sequence

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A terminator sequence is a nucleotide sequence in DNA which ends marks the end of a gene during Transcription. This sequence does this by providing signals that trigger the release of mRNA from the transcription complex. This then means that the mRNA can be spliced (if needed) and translated into proteins [1][2][3].

In prokaryotic genomes there are two classes of terminators, Rho-dependent and Rho-independent.

References:

  1. http://genesdev.cshlp.org/content/23/11/1247.full
  2. Patricia Richard and James L. Manley (2009), Transcription termination by nuclear RNA polymerases. Genes & Dev. 2009. 23: 1247-1269. doi: 10.1101/gad.1792809
  3. http://genesdev.cshlp.org/content/23/11/1247.full
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