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[[IP3|IP<sub>3</sub>]] ([[Inositol 1,4,5-trisphosphate|Inositol 1,4,5-trisphosphate]]) is a cleavage product of [[Phosphatidylinositol 4,5-bisphosphate|phosphatidylinositol 4,5-bisphosphate]] ([[Phosphatidylinositol 4,5-bisphosphate|PIP]]<sub>[[Phosphatidylinositol 4,5-bisphosphate|2]]</sub>). [[Phosphatidylinositol 4,5-bisphosphate|PIP]]<sub>[[Phosphatidylinositol 4,5-bisphosphate|2]]</sub> is a [[Phospholipid|phospholipid]] molecule cleaved into inositol 1,4,5-trisphosphate and [[Diacylglycerol|diacylglycerol]] ([[Diacylglycerol|DAG]]) by [[Phospholipase C|phospholipase C]] after hormone binding to the receptor. Inositol 1,4,5-trisphosphate binds to IP<sub>3</sub> receptor which results to the release of calcium from the [[Calcium pumps|calcium pumps]]. | [[IP3|IP<sub>3</sub>]] ([[Inositol 1,4,5-trisphosphate|Inositol 1,4,5-trisphosphate]]) is a cleavage product of [[Phosphatidylinositol 4,5-bisphosphate|phosphatidylinositol 4,5-bisphosphate]] ([[Phosphatidylinositol 4,5-bisphosphate|PIP]]<sub>[[Phosphatidylinositol 4,5-bisphosphate|2]]</sub>). [[Phosphatidylinositol 4,5-bisphosphate|PIP]]<sub>[[Phosphatidylinositol 4,5-bisphosphate|2]]</sub> is a [[Phospholipid|phospholipid]] molecule cleaved into inositol 1,4,5-trisphosphate and [[Diacylglycerol|diacylglycerol]] ([[Diacylglycerol|DAG]]) by [[Phospholipase C|phospholipase C]] after hormone binding to the receptor. Inositol 1,4,5-trisphosphate binds to [[IP3 receptor|IP]]<sub>[[IP3 receptor|3]]</sub>[[IP3 receptor|receptor]] which results to the release of calcium from the [[Calcium pumps|calcium pumps]]. | ||
see [[ | Also see [[Membrane transport|cell and membrane transport]] | ||
Revision as of 10:38, 9 November 2010
IP3 (Inositol 1,4,5-trisphosphate) is a cleavage product of phosphatidylinositol 4,5-bisphosphate (PIP2). PIP2 is a phospholipid molecule cleaved into inositol 1,4,5-trisphosphate and diacylglycerol (DAG) by phospholipase C after hormone binding to the receptor. Inositol 1,4,5-trisphosphate binds to IP3receptor which results to the release of calcium from the calcium pumps.
Also see cell and membrane transport