Inositol 1,4,5-trisphosphate

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Inositol 1,4,5-trisphospate, more well known as IP3 is a common secondary messenger molecule synthsised in the plasma membrane from the hydrolysis of phospholipid, PIP2, by phospholipase C. Its main role is in cell signalling pathways. IP3 is involved in the pathway for muscle contraction whereby calcium ions are release when IP3 binds to the receptor proteins on the sarcoplasmic reticulum in the muscle cell.  

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