Glycerine
Glycerine (also known as Glycerol or Glycerin) is a colourless, viscous, odourless fluid that is mainly used in pharmaceutical companies. Due to its sweet taste and low toxicity it is ideal for cough syrups and other medicines.
Structure
Glycerol contains 3 hydroxyl groups, which make it water soluble.
Its molecular formula is CH2(OH)CH(OH)CH2OH
Production
Glycerol is mainly produced as a byproduct in other processes, such as saponification of fats (soap making), as glycerol forms the core of triglycerides.
It is also produced as a byproduct in biodiesel production.
Metabolism
Gluconeogenisis occurs in the liver, and is when the body uses glycerol to make glucose in fasting conditions.
Glycerol is one of the 3 main carbon sources in the body for gluconeogenesis. The glycerol is released from the adipose stores of triacylglycerol and phosphorylated into glycerol-3-P. Glycerol-3-P is then converted to dihydroxyacetone-P, which then produces glucose [1].
References
- ↑ Marks, L., Marks' Basic Medical Biochemistry A Clinical Approach, 4th Edition, page 562.