Glycerine

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Glycerine (also known as Glycerol or Glycerin) is a colourless, viscous, oudourless fluid that is mainly used in pharmaceutical companies. Due to its sweet taste and low toxicity it is ideal for cough syrups and other medicines.


STURUCTURE

Glycerol contains 3 hydroxyl groups, these make it water soluble.

It's molecular formula is CH2(OH)CH(OH)CH2OH


PRODUCTION

Glycerol is mainly produced as a byproduct in other processes such as saponification of fats (soap making) as Glycerol forms the core of trigycerides.

It is also produced as a byproduct in biodiesel production.


METABOLISM

Gluconeogenisis in the liver is when the body uses Glycerol to make Glucose in fasting conditions.

Glycerol is one of the 3 main carbon sources in the body for gluconeogenisis. The Glycerol is released from the adipose stores of triacylglycerol and phosphorylated into Glycerol-3-P which is then converted to Dihydroxyacetone-P which goes onto produce Glucose. [1]

  1. Marks, L., Marks' Basic Medical Biochemistry A Clinical Approach, 4th Edition, page 562.