Rho dependent termination

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RNA polymerase stops transcribing DNA into RNA at terminator sequences. Rho dependent termation is one of the two types of termination. Rho factor is a helicase, composed of six identical subunits, that unwinds RNA-DNA and RNA-RNA duplexes. This unwinding is powered by the hydrolysis of nucleoside triphosphates. Rho binds to RNA and unzips DNA, weakening contacts on RNA-DNA duplexes favouring dissociation.

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