Krebs cycle

From The School of Biomedical Sciences Wiki
Revision as of 15:58, 8 January 2011 by 104097300 (talk | contribs) (Created page with '==== Introduction ==== The Krebs Cycle can also be called the Citric Acid Cycle (CAC) or the Tricarboxylic Acid (TCA) Cycle. This cycle takes place in the matrix of [[Mitochondr…')
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to navigation Jump to search

Introduction

The Krebs Cycle can also be called the Citric Acid Cycle (CAC) or the Tricarboxylic Acid (TCA) Cycle. This cycle takes place in the matrix of mitochondria and is the first step of aerobic processing in the cell. The process oxidises glucose derivatives as well as fatty acids and amino acids to carbon dioxide (CO2), most of which enter the cycle as acetyl coenzyme A. The purpose of the Krebs Cycle is to collect (eight) high-energy electrons from these fuels, which are carried by NADH and FADH2 to the electron transport chain. The Krebs Cycle is also the source of the precursors of many other molecules and is therefore amphibolic which means that it is both an anabolic and a catabolic pathway. [1]


The 8 Steps of the Krebs Cycle

(will be added shortly)

  1. Berg J.M, Tymoczko J.L, Stryer, L (2007). Biochemistry. 6th ed. New York: W. H. Freeman and Company. p475-476.