Glycerine

From The School of Biomedical Sciences Wiki
Revision as of 16:36, 23 October 2012 by Nnjm2 (talk | contribs)
Jump to navigation Jump to search

Glycerine (also known as Glycerol or Glycerin) is a colourless, viscous, oudourless fluid that is mainly used in pharmaceutical companies. Due to its sweet taste and low toxicity it is ideal for cough syrups and other medicines.

Structure

Glycerol contains 3 hydroxyl groups, these make it water soluble.

It's molecular formula is CH2(OH)CH(OH)CH2OH

Production

Glycerol is mainly produced as a byproduct in other processes such as saponification of fats (soap making) as glycerol forms the core of triglycerides.

It is also produced as a byproduct in biodiesel production.

Metabolism

Gluconeogenisis in the liver is when the body uses glycerol to make glucose in fasting conditions.

Glycerol is one of the 3 main carbon sources in the body for gluconeogenesis. The glycerol is released from the adipose stores of triacylglycerol and phosphorylated into glycerol-3-P which is then converted to dihydroxyacetone-P which goes onto produce glucose [1].

References

  1. Marks, L., Marks' Basic Medical Biochemistry A Clinical Approach, 4th Edition, page 562.