Bacterial artificial chromosome

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A Bacterial Artificial Chromosome (BAC) is larger than a regular plasmid. They are often used in PCR (Polymerase Chain Reaction) as they can take up larger inserts than a regular plasmid. DNA fragments of around 100-200 kb can be inserted into a BAC. A BAC is similar to an F' Plasmid[1]

References

  1. Molecular Biology of the Cell, Alberts et al, 5th Edition (2007) Garland Science, New York, Chapter 8, Page 541

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