A polypeptide is a polymer which is linear and consists of many amino acids bonded together via condensation reactions that result in peptide bonds between the amino acids, which are examples of covalent bonds. The polymer chain also contains two terminals; the carboxyl-terminal at the end with a free carboxyl group and an amino-terminal at the end with a free amino group.
The amino acids contained within polypeptides themselves are coded for by codons which are also part of a polymer known as messenger RNA, the process of which is known as translation. However, before translation can occur, messenger RNA must be synthesized via complementary base pairing during transcription. This is dictated by the sequence of codons within DNA.
- ↑ Lubert Stryer, Biochemistry, fourth edition, W.H Freeman and Company New York 1955.