Pyrophosphate

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The 2 phosphoryl deposits of UTP given off in the reaction to synthesise UDP-glucose from glucose 1-phosphate and UTP. The reaction is catalysed by UDP-glucose pyrophosphorylase, and the reaction is reversible. Pyrophosphate is hydrolised by pyrophosphatase to orthophosphate and this encourages UDP - glucose synthesis [1][2].

References

  1. Berg J., Tymoczko J and Stryer L. (2007) Biochemistry, 6th edition, New York: WH Freeman.
  2. Berg J., Tymoczko J and Stryer L. (2007) Biochemistry, 6th edition, New York: WH Freeman. Pages 649 - 650


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