Vibrio cholerae

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Vibreo cholerae is a gram-negative bacterium which is both fermentative and oxidative in its metabolism. Its movement is enbled by a single polar flagellum[1].

There are hundreds of strains of V. cholerae, and only those which are infected by a mobile bacteriophage cause human disease such as the epidemic diarrheal disease, cholera[2]. V. cholerae causes cholera by producing cholera toxins (CT) which consists of 2 subunits: A and B. The A subunit contains enzymatic activity and the B subunit binds to a cell-surface receptor called GM1 on intestinal epithelial cells[3].

References

  1. www.textbookofbacteriology.net,2008,Vibreo cholerae and Asiatic cholera, Kenneth Todar
  2. Alberts B, Johnson A, Lewis J, Morgan D, Raff M, Roberts K, Walter P. Molecular Biology of the Cell. 6th Ed, Garland Science, Taylor and Francis Group. 2015; Page 1269-1270
  3. Alberts B, Jonhson A, Lewis J, Morgan D, Raff M, Roberts K, Walter P. Molecular Biology of the Cell. 6th Ed, Garland Science, Taylor and Francis Group. 2015; Page 576
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