Glut 4

Glut4 is a member of the Solute Carrier Family 2 (SLCA2). The protein is encoded by the SLC2A4 gene and is involved in the insulin-dependent trafficking of glucose to the plasma membrane. The protein is crucial to glucose transport and genetic mutations can be involved in Non-Insulin Dependent Diabetes Mellitus (Diabetes). Glut4 is typically found in skeletal and cardiac muscle, as well as adipose tissue.

In Diabetes, Glut4 mRNA and protein levels decreases in both white and brown adipose tissue.

Also see Glut transporter.