Co-enzyme: Difference between revisions
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A coenzyme is a [[Molecule|molecule]] which helps the functioning and activity of an [[Enzyme|enzyme]] by binding and therefore activating it to form the [[Holoenzyme|holoenzyme]]<ref>Medicine Net, Coenzymes, https://www.medicinenet.com/script/main/art.asp?articlekey=13153</ref>. Coenzymes are nonpolypeptide small [[Molecules|molecules]] or ions that are bound in the [[Active site|active site]], and can be chemically modified during the reaction so need to be replaced or regenerated afterwards<ref>Lodish H, Kaiser CA, Bretcher A, Amon A, Berk A, Kneger M, Ploegh H, Scott MP. Molecular Cell Biology. 7th Ed, New York: W.H. Freeman and Company. 2013.</ref>. Examples include [[NAD+|NAD+]] (nicotinamide adenine dinucleotide), [[FAD|FAD]] (flavin adenine dinucleotide) and [[Haem group|haem groups]] that bind [[Oxygen|oxygen]] in [[Haemoglobin|haemoglobin]]<ref>Lodish H, Kaiser CA, Bretcher A, Amon A, Berk A, Kneger M, Ploegh H, Scott MP. Molecular Cell Biology. 7th Ed, New York: W.H. Freeman and Company. 2013.</ref>. | A coenzyme is a [[Molecule|molecule]] which helps the functioning and activity of an [[Enzyme|enzyme]] by binding and therefore activating it to form the [[Holoenzyme|holoenzyme]]<ref>Medicine Net, Coenzymes, https://www.medicinenet.com/script/main/art.asp?articlekey=13153</ref>. Coenzymes are nonpolypeptide small [[Molecules|molecules]] or ions that are bound in the [[Active site|active site]], and can be chemically modified during the reaction so need to be replaced or regenerated afterwards<ref>Lodish H, Kaiser CA, Bretcher A, Amon A, Berk A, Kneger M, Ploegh H, Scott MP. Molecular Cell Biology. 7th Ed, New York: W.H. Freeman and Company. 2013.</ref>. Examples include [[NAD+|NAD<sup>+</sup>]] (nicotinamide adenine dinucleotide), [[FAD|FAD]] (flavin adenine dinucleotide) and [[Haem group|haem groups]] that bind [[Oxygen|oxygen]] in [[Haemoglobin|haemoglobin]]<ref>Lodish H, Kaiser CA, Bretcher A, Amon A, Berk A, Kneger M, Ploegh H, Scott MP. Molecular Cell Biology. 7th Ed, New York: W.H. Freeman and Company. 2013.</ref>. | ||
=== References === | === References === | ||
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Revision as of 16:11, 4 December 2017
A coenzyme is a molecule which helps the functioning and activity of an enzyme by binding and therefore activating it to form the holoenzyme[1]. Coenzymes are nonpolypeptide small molecules or ions that are bound in the active site, and can be chemically modified during the reaction so need to be replaced or regenerated afterwards[2]. Examples include NAD+ (nicotinamide adenine dinucleotide), FAD (flavin adenine dinucleotide) and haem groups that bind oxygen in haemoglobin[3].
References
- ↑ Medicine Net, Coenzymes, https://www.medicinenet.com/script/main/art.asp?articlekey=13153
- ↑ Lodish H, Kaiser CA, Bretcher A, Amon A, Berk A, Kneger M, Ploegh H, Scott MP. Molecular Cell Biology. 7th Ed, New York: W.H. Freeman and Company. 2013.
- ↑ Lodish H, Kaiser CA, Bretcher A, Amon A, Berk A, Kneger M, Ploegh H, Scott MP. Molecular Cell Biology. 7th Ed, New York: W.H. Freeman and Company. 2013.