Factor independent termination: Difference between revisions
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RNA [[ | RNA [[Polymerase|polymerase]] stops transcribing [[DNA|DNA]] into [[RNA|RNA]] at [[Terminator sequence|terminator sequences]], factor independent termation one of the two types of termination. Factor independent terminators have a series of 4 to 10 consecutive [[Adenine|A]]-[[Thymine|T]] base pairs and a [[Guanine|G]] and [[Cytosine|C]] rich region with a [[Palindromic sequence|palindromic sequence]] that immediately preceeding the series of A-T base pairs. This palindromic region forms a stem loop leaving the RNA and DNA connected only by the few A - U and T - A base pairs, these are the weaker [[Watson-Crick_pairs]] as they only have 2 [[Hydrogen_bonds]] connecting them, this reduced affinity favours dissociation of the RNA and DNA [[template strand]]. | ||
Latest revision as of 10:34, 2 December 2011
RNA polymerase stops transcribing DNA into RNA at terminator sequences, factor independent termation one of the two types of termination. Factor independent terminators have a series of 4 to 10 consecutive A-T base pairs and a G and C rich region with a palindromic sequence that immediately preceeding the series of A-T base pairs. This palindromic region forms a stem loop leaving the RNA and DNA connected only by the few A - U and T - A base pairs, these are the weaker Watson-Crick_pairs as they only have 2 Hydrogen_bonds connecting them, this reduced affinity favours dissociation of the RNA and DNA template strand.