Oxidative decarboxylation: Difference between revisions
Jump to navigation
Jump to search
Created page with "Oxidative decarboxylation is a process in which carbon dioxide is produced through the removal of a carbon group as a result of oxidation reactions<ref>Voet, Donald..." |
No edit summary |
||
| Line 1: | Line 1: | ||
Oxidative decarboxylation is a process in which carbon dioxide is produced through the removal of a carbon group as a result of [[Oxidation|oxidation ]] | Oxidative decarboxylation is a process in which carbon dioxide is produced through the removal of a carbon group as a result of [[Oxidation|oxidation reactions]].<ref>Voet, Donald; Voet, Judith; Pratt, Charlotte (2013). Fundamentals of Biochemistry (4 ed.). John Wiley and Sons.</ref><span style="line-height: 1.5em;"> There are vital in many biological processes such as the </span>[[Citric acid cycle|citric acid cycle]]<span style="line-height: 1.5em;">. </span> | ||
In the [[ | In the [[Citric acid cycle|citric acid cycle]] it is used three times to generate CO<sub>2</sub><sub> </sub>whilst also reducing [[NAD+|NAD]]<sup>[[NAD+|+]] </sup>to [[NADH|NADH]]. Firstly, pyruvate is converted by a [[Pyruvate Dehydrogenase Complex|pyruvate dehydrogenase]] complex to [[Acetyl CoA|Acetyl CoA]].[[Acetyl CoA|<ref>Berg J.M, Tymoczko J.L, Stryer, L (2007). Biochemistry. 6th ed. New York: W. H. Freeman and Company. p477</ref>]]<span style="line-height: 1.5em;"> Secondly, using the enzyme </span>[[Isocitrate dehydrogenase|Isocitrate dehydrogenase]]<span style="line-height: 1.5em;"> to </span>[[Α-Ketoglutarate|α-Ketoglutarate<ref>Berg J.M, Tymoczko J.L, Stryer, L (2007). Biochemistry. 6th ed. New York: W. H. Freeman and Company.</ref>]]<span style="line-height: 1.5em;"> and finally </span>[[Α-Ketoglutarate dehydrogenase|α-Ketoglutarate dehydrogenase]]<span style="line-height: 1.5em;"> is used to convert</span>[[Α-Ketoglutarate| α-Ketoglutarate]]<span style="line-height: 1.5em;"> to </span>[[Succinyl CoA|Succinyl CoA]]<span style="line-height: 1.5em;">.</span>[[Succinyl CoA|<ref>Berg J.M, Tymoczko J.L, Stryer, L (2007). Biochemistry. 6th ed. New York: W. H. Freeman and Company. p485</ref>]] | ||
=== References === | <br> | ||
=== References === | |||
<references /> | <references /> | ||
Revision as of 16:14, 27 November 2014
Oxidative decarboxylation is a process in which carbon dioxide is produced through the removal of a carbon group as a result of oxidation reactions.[1] There are vital in many biological processes such as the citric acid cycle.
In the citric acid cycle it is used three times to generate CO2 whilst also reducing NAD+ to NADH. Firstly, pyruvate is converted by a pyruvate dehydrogenase complex to Acetyl CoA.[2] Secondly, using the enzyme Isocitrate dehydrogenase to α-Ketoglutarate[3] and finally α-Ketoglutarate dehydrogenase is used to convert α-Ketoglutarate to Succinyl CoA.[4]
References
- ↑ Voet, Donald; Voet, Judith; Pratt, Charlotte (2013). Fundamentals of Biochemistry (4 ed.). John Wiley and Sons.
- ↑ Berg J.M, Tymoczko J.L, Stryer, L (2007). Biochemistry. 6th ed. New York: W. H. Freeman and Company. p477
- ↑ Berg J.M, Tymoczko J.L, Stryer, L (2007). Biochemistry. 6th ed. New York: W. H. Freeman and Company.
- ↑ Berg J.M, Tymoczko J.L, Stryer, L (2007). Biochemistry. 6th ed. New York: W. H. Freeman and Company. p485