Nucleoside triphosphate: Difference between revisions

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<span style="line-height: 1.5em;">Nucleoside triphosphates are monomers of [[Rna|RNA]] and [[DNA|DNA]] and are made up of a [[Nucleoside|nucleoside]] and 3 phosphate groups. A [[Nucleoside|nucleoside]] is a molecule containing a [[Nitrogenous base|nitrogenous base]] and a sugar, either [[Ribose|ribose]] or [[Deoxyribose|deoxyribose]]. The nucleoside triphosphates containing [[Ribose|ribose]] are&nbsp;</span><span style="line-height: 19.9200000762939px;">[[ATP|ATP]], [[CTP|CTP]], [[GTP|GTP]], [[UTP|UTP]] and m</span><sup style="line-height: 19.9200000762939px;">5</sup><span style="line-height: 19.9200000762939px;">UTP <ref>Academic Dictionaries and Encyclopedias (2010) Nucleoside Triphosphate [Internet], Available from http://en.academic.ru/dic.nsf/enwiki/425004#sel= [Accessed 21/10/2014].</ref>. These NTPs, excluding m</span><sup style="line-height: 19.9200000762939px;">5</sup><span style="line-height: 19.9200000762939px;">UTP, act as building blocks for [[Transcription|transcription]] in producing [[MRNA|mRNA]] <ref>Alberts, B et al. (2008). Molecular Biology of the Cell. 5th ed. New York: Garland Science. 334.</ref>. NTPs with [[Deoxyribose|deoxyribose]] in place of [[Ribose|ribose]],&nbsp;</span><span style="line-height: 19.9200000762939px;">also know as the [[DNTP|dNTPs]], include [[DATP|dATP]], [[DCTP|dCTP]], [[DGTP|dGTP]], [[DTTP|dTTP]], [[DUTP|dUTP]] <ref>Academic Dictionaries and Encyclopedias (2010) Nucleoside Triphosphate [Internet], Available from: http://en.academic.ru/dic.nsf/enwiki/425004#sel= [Accessed 21/10/2014)</ref>.&nbsp;</span><span style="line-height: 19.9200000762939px;">These molecules, except for [[DUTP|dUTP]], are required for [[Dna replication|DNA replication]] where energy is released from [[Hydrolysis|hydrolysing]] the phosphate groups. This energy is necessary for the reaction to progress <ref>Alberts, B et al. (2008). Molecular Biology of the Cell. 5th ed. New York: Garland Science. 266-267.</ref>.&nbsp;</span>
Nucleoside triphosphates are monomers of [[RNA|RNA]] and [[DNA|DNA]] and are made up of a [[Nucleoside|nucleoside]] and 3 phosphate groups. A [[Nucleoside|nucleoside]] is a molecule containing a [[Nitrogenous base|nitrogenous base]] and a sugar, either [[Ribose|ribose]] or [[Deoxyribose|deoxyribose]]. The nucleoside triphosphates containing [[Ribose|ribose]] are [[ATP|ATP]], [[CTP|CTP]], [[GTP|GTP]], [[UTP|UTP]] and m<sup>5</sup>UTP <ref>Academic Dictionaries and Encyclopedias (2010) Nucleoside Triphosphate [Internet], Available from http://en.academic.ru/dic.nsf/enwiki/425004#sel= [Accessed 21/10/2014].</ref>. These NTPs, excluding m<sup>5</sup>UTP, act as building blocks for [[Transcription|transcription]] in producing [[MRNA|mRNA]] <ref>Alberts, B et al. (2008). Molecular Biology of the Cell. 5th ed. New York: Garland Science. 334.</ref>. NTPs with [[Deoxyribose|deoxyribose]] in place of [[Ribose|ribose]], also know as the [[DNTP|dNTPs]], include [[DATP|dATP]], [[DCTP|dCTP]], [[DGTP|dGTP]], [[DTTP|dTTP]], [[DUTP|dUTP]] <ref>Academic Dictionaries and Encyclopedias (2010) Nucleoside Triphosphate [Internet], Available from: http://en.academic.ru/dic.nsf/enwiki/425004#sel= [Accessed 21/10/2014)</ref>. These molecules, except for [[DUTP|dUTP]], are required for [[Dna replication|DNA replication]] where energy is released from [[Hydrolysis|hydrolysing]] the phosphate groups. This energy is necessary for the reaction to progress <ref>Alberts, B et al. (2008). Molecular Biology of the Cell. 5th ed. New York: Garland Science. 266-267.</ref>.  


=== <span style="line-height: 19.9200000762939px;" />References ===
=== References ===


<span style="line-height: 19.9200000762939px;"><references /></span>
<references />

Latest revision as of 11:08, 28 November 2014

Nucleoside triphosphates are monomers of RNA and DNA and are made up of a nucleoside and 3 phosphate groups. A nucleoside is a molecule containing a nitrogenous base and a sugar, either ribose or deoxyribose. The nucleoside triphosphates containing ribose are ATP, CTP, GTP, UTP and m5UTP [1]. These NTPs, excluding m5UTP, act as building blocks for transcription in producing mRNA [2]. NTPs with deoxyribose in place of ribose, also know as the dNTPs, include dATP, dCTP, dGTP, dTTP, dUTP [3]. These molecules, except for dUTP, are required for DNA replication where energy is released from hydrolysing the phosphate groups. This energy is necessary for the reaction to progress [4].

References

  1. ↑ Academic Dictionaries and Encyclopedias (2010) Nucleoside Triphosphate [Internet], Available from http://en.academic.ru/dic.nsf/enwiki/425004#sel= [Accessed 21/10/2014].
  2. ↑ Alberts, B et al. (2008). Molecular Biology of the Cell. 5th ed. New York: Garland Science. 334.
  3. ↑ Academic Dictionaries and Encyclopedias (2010) Nucleoside Triphosphate [Internet], Available from: http://en.academic.ru/dic.nsf/enwiki/425004#sel= [Accessed 21/10/2014)
  4. ↑ Alberts, B et al. (2008). Molecular Biology of the Cell. 5th ed. New York: Garland Science. 266-267.
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